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Symbol
Name
ID

Sirt1
sirtuin 1
MGI:2135607

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes		immune system phenotype	increased basophil cell number	decreased CD8-positive, alpha-beta T cell number	increased immunoglobulin level	increased autoantibody level	increased anti-nuclear antigen antibody level	increased susceptibility to endotoxin shock	glomerulonephritis	lung inflammation	interstitial pneumonia
Availability	Mouse Genotype	immune system phenotype	increased basophil cell number	decreased CD8-positive, alpha-beta T cell number	increased immunoglobulin level	increased autoantibody level	increased anti-nuclear antigen antibody level	increased susceptibility to endotoxin shock	glomerulonephritis	lung inflammation	interstitial pneumonia
	Sirt1^tm1Fwa/Sirt1^tm1Fwa	*
	Sirt1^tm1Mcby/Sirt1^tm1Mcby
	Sirt1^{tm1b(EUCOMM)Wtsi}/Sirt1⁺
	Tg(Sirt1)ASrn/?

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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